Can Benzodiazepines Like Anxiolytic Drugs Cause Cancer?

Benzodiazepines are nothing but a group of sedatives that are widely prescribed and that include Xanax, Valium, Ambien etc. These drugs are commonly taken for anxiety or insomnia, often for a longer period of time.

Xanax, Valium, and Ambien are the few names in the Benzodiazepines category because these all have a structural similarity (which is composed of the benzene ring attached to another ring of seven heterocyclic members called Diazepine).

Cure Your Anxiety the Right Way

Benzodiazepines are the depressants of the nervous system, acting, in particular, on the limbic system. They are part of the Gamma-Aminobutyric Acid (GABA) complex which is a Neurotransmitter with inhibitory action and its receptors are part of an inhibitory action mediated by GABA.

The benzodiazepine receptors are distributed throughout the brain and spinal cord; they are also found in the adrenal glands, kidneys, pineal gland and platelets. Benzodiazepines have rapid and high absorption and are not degraded before their arrival in the central nervous system.

Benzodiazepines can be administered orally, intramuscularly and intravenously. The lifespan of these drugs varies from 2 hours to 74 hours. Short-acting compounds have better hypnotic results, while long-acting compounds are preferred for their anxiolytic effects.

Take Benzodiazepines the Right Way

Uses of Benzodiazepines

It’s used to treat anxiety, insomnia, alcohol withdrawal, epilepsy, affective disorders, also to treat poisonings with certain drugs.

Types of Benzodiazepines

Usually ends in -lam, -lan, -pam, -pan: Lorazepam, Diazepam (also known as Valium), Clonazepam, Triazolam etc. within this group are classified according to their average life duration in the body.

Effects of the Benzodiazepines

They act as sedatives, hypnotics, muscle relaxants, anticonvulsants, anxiolytics, and amnesia.

Chemical Structure of Benzodiazepines
Chemical Structure of Benzodiazepines

What are the Negative Effects of Benzodiazepines?

Dangerous… I repeat… An overdose of Benzodiazepines, particularly when combined with alcohol or any other types of sedative drugs, can even lead to a coma. The antidote for all benzodiazepines is flumazenil. The symptoms are excessive drowsiness, respiratory depression, confused speech, bradycardia, and hypotension.

There are various side-effects of the drug Benzodiazepine too. The side-effects include:

  • Drowsiness
  • Vertigo
  • Stomach ache
  • Blurred vision
  • A headache
  • Confusion
  • Depression
  • Coordination disorder
  • Temblor
  • Weakness
  • Antegrade amnesia
  • Hangover effect
  • Unusual dreams
  • Nightmares
  • Pain in the chest
  • Jaundice
  • Paradoxical reactions
  • Cross-tolerance (Alcohol)

While benzodiazepines are very effective in the short term (two to four weeks) the side effects associated with long-term use (deficiencies in cognitive abilities, memory problems, mood swings, overdoses when combined with other drugs) can make the risk-benefit ratio wrong.

Other symptoms that may occur are emotional dullness, nausea, headache, dizziness, irritability, lethargy, sleep problems, memory problems, personality changes, aggression, depression, agoraphobia, anxiety and panic attacks, social deterioration and problems labor If consumption is discontinued, the effects of long-term consumption may disappear after 3 or 6 months.

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Conclusion

After reading all the above explanations, you must have understood the risks involved in taking Benzodiazepines for a longer (more than 12 months) period of time.

Can Benzodiazepines Cause Cancer?

Prolonged use increases the risk of developing Alzheimer and even Cancer from an increase in the cases of people with insomnia who use these drugs to sleep, according to neurologists.

The doses and frequency vary for every person to person.  These variations may be on the basis of age, sex, allergies, and any other kind of diseases.

Uncontrolled uses of this drug benzodiazepines can cause any kind of disastrous health hazards. It can make you so addicted that it can even become almost impossible for you to leave it.

Benzodiazepines (Xanax, Valium, Ambien etc.) are not recommended without the medical guidance of any doctor.

Modern Technology Advancements for the Treatment of Cancer

Cancer is the disease which every other person is concerned about these days. If you take a survey, you would realize that there are quite a number of people suffering from this disease at a point in time.

There are a lot of treatments available for cancer these days that are making use of the latest technology to make use of this disease. People from all over the world and scholars from various universities have been trying various methods to treat cancer.

In the recent past, there have been various advancements in the treatment of cancer.

Best Technological Advancements in the Field of Cancer Treatment

  • Intensity Modulated Radiation Therapy (IMRT)

Intensity Modulated Radiation Therapy (IMRT)

This kind of therapy is capable of treating a number of cancer types. It allows radiation oncologists to use higher doses of radiation to cancer cells but limit the exposure to the normal tissues and cells at a minimum.

  • Linear Accelerators

Linear Accelerators

This treatment method enables oncologists to bombard the cancer cells with higher amounts of radiation but in a very controlled way.

The machine makes use of a computerized tool to shape up the radiation according to the treatment plan for the particular patient.

This tool is devised in such a manner that the radiation moves continuously and also change the intensity and the shape of the beam so as to fit the requirement of the patient as per their treatment plan as well as the size and the shape of the tumor so that maximum can be obtained out of it.

  • Image Guided Radiation Therapy

Image Guided Radiation Therapy

It can be used for both tumor controlled radiation as well as sparing the normal tissues from damage due to the effect of the radiation. It can effectively shape up the radiation to suit the shape of the tumor cell and also bombard the malignant tumor cells with higher doses of radiation, however, ensuring that the normal cells around the tumorous tissue are not harmed even the slightest.

A thing about the tumors is that it can move during a treatment and from one treatment session to the next as a result of the normal internal organs and hence it even the smallest differences in the way of the treatment is taken care of.

  • (HDR) High Dose Rate Brachytherapy

(HDR) High Dose Rate Brachytherapy

This therapy is another mode of targeting the tumor cells directly with the high dose rate of radio waves and not affecting the adjacent cells and organs.

The radioactive source travels to the target site with the help of a catheter

  • 3-Dimensional Conformal Radiation Therapy

3-Dimensional Conformal Radiation Therapy

This makes use of the CT simulator which helps the physician to map and pinpoint the target.

Simulations can be performed very easily and quickly and with more efficiency. Furthermore, the procedure is also a patient compliant method.


The clinical application of the new technology allows treating lung, liver, bone and prostate tumors, among others, with the utmost precision in the administration of the treatment.

This precision, together with the possibility of applying high and highly curative doses, translates into a notable decrease in the sessions needed for treatment.

All this said and done there are new avenues to treat cancer and specially customize the treatment program on the basis of the requirement and the compliance ability of the patient.

These new treatment methods for cancer also ensure that more people suffering from the disease can be treated at large.

Prostate Cancer Prevention Guide

Preventing cancer is basically taking steps to reduce the chance of experiencing this disease. With prevention decreases the number of new cases in a group of people and this in turn reduces the number of deaths caused by cancer.

Some cancer risk factors can be avoided, but many others can not. For example, both smoking and certain inherited genes are risk factors for some types of cancer, but smoking can only be avoided.

Prevention Guide for Prostate Cancer

Regular exercise and healthy eating are recommendations to avoid for some types of cancer. To prevent it is necessary to analyze the risk factors and the recommendations that must be followed to avoid it, that is why today we share everything you need to know about prevention and risk factors in prostate cancer:

Forms of prevention:

  • Change the lifestyle or eating habits.
  • Avoid things that are known to cause cancer.
  • Take medicines to treat a precancerous condition or to prevent cancer from starting.

Tips-to-Prevent-Prostate-Cancer

Risk factor’s:

  • Prostate cancer is rare in men under 50 years of age. The probability of developing prostate cancer increases with the age of men.
  • Family history of prostate cancer. A man whose father, brother or son has had prostate cancer is at a higher than average risk for this cancer.
  • Prostate cancer occurs more frequently in African-American men than in white men. African-American men with prostate cancer are more likely to die from this disease than white men.
  • The prostate needs male hormones to function correctly. The main male sex hormone is testosterone. This helps the body to develop and maintain male sexual characteristics. An enzyme in the body converts testosterone to dihydrotestosterone (DHT). DHT is important for normal growth of the prostate, but it can also make the prostate grow larger and play a role in the progression of prostate cancer.

prostate-gland-large

The following protective factors may decrease the risk of prostate cancer:

Folate is a type of vitamin B that is naturally contained in some foods, such as vegetables, beans, and orange juice. Folic acid is a form of folate produced by man that is found in vitamin supplements and fortified foods, such as breads and whole grains.

Finasteride and dutasteride. They are medicines that are used to decrease the amount of male sex hormones made by the body. These drugs impede the action of the enzyme that converts testosterone to dihydrotestosterone (DHT).

Final Words

Remember that before any anomaly that you detect in your body it is important to go to the doctor. However, you do not have to wait until this happens.

Perform routine exams and share the message with those you love most so that together we can take care of our Health.

Know Everything About the Prostate Cancer

It’s horrible… Yes, the prostate cancer is horrible. You must know the symptoms and prevention of the prostate cancer.

What is the Prostate Cancer?

Prostate cancer is a disease that gets developed mainly in older men. As men age, the prostate may enlarge and block the urethra or bladder. This can cause difficulty urinating or interfering with sexual function.

diagram-of-localised-prostate-cancer

The problem is known as benign prostatic hyperplasia, which often requires surgery to correct it. The symptoms of benign prostatic hyperplasia or other problems that affect the gland may be similar to the symptoms of prostate cancer.

Prostate cancer is the most frequent of all cancers among men.

What are the Risk Factors for the Prostate Cancer?

  • Age: Age is the main risk factor for prostate cancer. The risk of developing prostate cancer begins to increase from 50 years of age in white men and from 40 years of age in black men or with a family history (father or brother) of prostate cancer. Almost two out of three cases of prostate cancer are detected in men older than 65 years.
  • Race: Prostate cancer is more common in black men than in men of other races. In addition, black men are more likely to be diagnosed at an advanced stage, and are more than twice as likely to die of prostate cancer compared to white men. On the other hand, the lowest rate of prostate cancer is observed in individuals of Asian race.
  • Family history: The risk of prostate cancer is strongly influenced by family history. Those men who have a first-degree relative (father or brother) diagnosed with prostate cancer are more likely to develop the disease. Only 5-10% of prostate cancers have a hereditary component.
    In hereditary prostate cancer, the age of onset of cancer is earlier (before 55 years) and patients often have first-degree relatives with prostate cancer. Genes involved in increased susceptibility to the development of prostate cancer have been discovered.
  • Diet: Recent studies suggest that high consumption of animal fats may increase the risk of prostate cancer.
    On the other hand, supplements of vitamin E and selenium and high consumption of lycopene could have a protective effect in some prevention studies (see below).
  • Obesity: Most studies have not found that obesity is associated with an increased risk of developing prostate cancer.
  • Exercise: in most studies, exercise has not been shown to reduce the risk of prostate cancer.
  • Alcohol: There does not seem to be a correlation between alcohol intake and the incidence of prostate cancer, although its high consumption increases the risk of more aggressive cancer.
  • Coffee: High coffee consumption seems to be associated with a lower incidence of more advanced prostate cancer.
  • Tobacco: Smoking has been associated with an increase in the incidence, as well as an increased risk of relapse after diagnosis.
  • Infection and inflammation of the prostate: Some studies have suggested that prostatitis (inflammation of the prostate gland) may be associated with an increased risk of prostate cancer, although other studies have not found such an association.
Breast Cancer VS Prostate Cancer
Source: American Cancer Society

Is it possible to prevent prostate cancer?

– Tomatoes (raw, cooked or tomato-containing products such as sauces) and watermelons are high in lycopene . These substances are antioxidants that help prevent DNA damage. Some preliminary studies suggest that lycopene may help reduce the risk of prostate cancer, although a more recent study found no association between lycopene blood levels and the risk of prostate cancer. The investigations on the subject continue.

– To study the possible effects of selenium and vitamin E on the risk of prostate cancer, several researchers conducted a study called Selenium and Vitamin E Cancer Prevention Trial (SELECT). In this clinical study, about 35,000 men were chosen at random to take one or both of these supplements or a placebo. After an average of five years of daily use, none of the supplements demonstrated a reduction in the risk of prostate cancer.

– Several studies are currently looking at the possible effects of soy derivatives (isoflavones) on the risk of prostate cancer, although it seems that their intake could reduce the incidence of prostate cancer.

– In a study that was conducted in men at high risk of developing prostate cancer, the administration of the drug Finasteride managed to reduce the risk of prostate cancer by 25% compared with a placebo.

However, this medication causes side effects such as decreased sex drive and impotence. On the other hand, it improves the urinary symptoms associated with prostatic hyperplasia. A higher rate of high-grade tumors (which have a worse prognosis) was also observed in the patients who took the drug in the study.

With all this, the use of this drug can not be recommended as a preventive agent. Other clinical studies are underway with other drugs that may play a role in the prevention of prostate cancer.